# Cashmere Cream > Cashmere Cream is a compounded prescription cream that combines tretinoin, a retinoid, with caffeine, GHK-Cu (a copper peptide) and niacinamide, so four ingredients take one step in your routine. Because it contains a retinoid, it isn't used with another retinoid unless your care team says so. - Category: Skin care - Prescription required: Yes, after review by a licensed clinician - Last updated: 2026-10-08 - Canonical URL: https://increase.health/treatments/cashmere-cream - Start an assessment: https://start.increase.health/skin-care/questionnaire ## Key facts - **Ingredients:** Tretinoin (a retinoid), caffeine, GHK-Cu, niacinamide - **How it's used:** Applied topically, as your care team directs - **Price:** $705 one-time for a 3-month supply - **Prescription:** Required, after clinician review - **FDA status:** Compounded; not FDA-approved Cashmere Cream combines tretinoin, a topical retinoid, with caffeine, GHK-Cu and niacinamide in a single prescription cream. Because it contains tretinoin, it takes the place of any other retinoid and is not a moisturiser to layer over other treatments. Apply it to completely dry skin, and wear SPF 30+ every morning. Your care team decides how often you use it and how it fits with anything you already use. Each order is compounded to your prescription and shipped in a plain tube. ## Frequently asked questions ### What is Increase Health? Increase Health is an online clinic and pharmacy for weight optimization, peptide therapy and prescription skin care. Licensed U.S. providers review your intake, prescribe when appropriate and adjust your protocol over time. ### Where are telehealth services available? Telehealth services may be available in all 50 states where clinically appropriate and permitted by applicable law. Clinical care is provided by licensed medical providers affiliated with an independent physician group. ### Is treatment guaranteed? No. Completing an intake form or selecting a program does not guarantee treatment. Prescription medications are only provided when a licensed medical provider determines they are clinically appropriate. ### Do I need to speak with a provider? Your intake is reviewed by a licensed medical provider. Depending on your health history, goals, treatment request, and applicable requirements, the provider may request additional information, lab work, or a consultation before making a treatment decision. ### Are compounded medications FDA-approved? No. Compounded medications are not FDA-approved. The FDA does not evaluate compounded medications for safety, effectiveness, or quality. ### Can I use Increase Health for emergency care? No. Increase Health is not for emergencies. If you are experiencing a medical emergency, call 911 or seek immediate medical attention. ### Who provides the clinical care? Licensed medical providers affiliated with an independent physician group. ### Who handles pharmacy and prescription fulfillment? Prescriptions are prepared and dispensed by state-licensed U.S. compounding pharmacies. ## Important safety information Contains tretinoin, a retinoid. Dryness, peeling and mild stinging are expected in the first weeks. Don't combine it with another retinoid unless your care team says so, and don't use it if you are pregnant, planning pregnancy or breastfeeding. Reduce use if irritation is severe and message your care team. ## References 1. [Compounding and the FDA: Questions and Answers](https://www.fda.gov/drugs/human-drug-compounding/compounding-and-fda-questions-and-answers), U.S. Food and Drug Administration --- Increase Health connects patients with independent, US-licensed clinicians. Compounded medications are not FDA-approved. This content is informational and not a substitute for medical advice.