# Tretinoin > Tretinoin is a prescription retinoid, a stronger vitamin A derivative than over-the-counter retinol, that speeds up skin cell turnover. It is commonly prescribed for acne and signs of sun damage. You apply a pea-sized amount at night, starting two nights a week and building up, with your provider guiding the pace. - Category: Skin care - Generic name: tretinoin - Prescription required: Yes, after review by a licensed clinician - Last updated: 2026-10-08 - Canonical URL: https://increase.health/treatments/tretinoin - Start an assessment: https://start.increase.health/skin-care/questionnaire ## Key facts - **Active ingredient:** Tretinoin (a retinoid) - **How it's used:** Thin layer applied topically at night - **Retinol vs tretinoin:** Retinol is OTC and converts to retinoic acid; tretinoin is retinoic acid - **Price:** $345 one-time for a 3-month supply - **Prescription:** Required, after clinician review Tretinoin is a topical retinoid that acts on skin cell turnover, and one of the most widely studied ingredients in dermatology. Start two nights a week on completely dry skin, with a pea-sized amount for the whole face, and build up from there. A bland moisturiser helps in the first month, and SPF 30+ every morning is part of the plan. Your provider picks the cream or gel to suit your skin history and adjusts your routine as your skin adapts. Each order is compounded fresh and shipped in an opaque, air-tight container. ## Frequently asked questions ### What is Increase Health? Increase Health is an online clinic and pharmacy for weight optimization, peptide therapy and prescription skin care. Licensed U.S. providers review your intake, prescribe when appropriate and adjust your protocol over time. ### Where are telehealth services available? Telehealth services may be available in all 50 states where clinically appropriate and permitted by applicable law. Clinical care is provided by licensed medical providers affiliated with an independent physician group. ### Is treatment guaranteed? No. Completing an intake form or selecting a program does not guarantee treatment. Prescription medications are only provided when a licensed medical provider determines they are clinically appropriate. ### Do I need to speak with a provider? Your intake is reviewed by a licensed medical provider. Depending on your health history, goals, treatment request, and applicable requirements, the provider may request additional information, lab work, or a consultation before making a treatment decision. ### Are compounded medications FDA-approved? No. Compounded medications are not FDA-approved. The FDA does not evaluate compounded medications for safety, effectiveness, or quality. ### Can I use Increase Health for emergency care? No. Increase Health is not for emergencies. If you are experiencing a medical emergency, call 911 or seek immediate medical attention. ### Who provides the clinical care? Licensed medical providers affiliated with an independent physician group. ### Who handles pharmacy and prescription fulfillment? Prescriptions are prepared and dispensed by state-licensed U.S. compounding pharmacies. ## Important safety information Dryness, peeling and mild stinging are expected in the first weeks. Reduce frequency if irritation is severe and message your provider. --- Increase Health connects patients with independent, US-licensed clinicians. Compounded medications are not FDA-approved. This content is informational and not a substitute for medical advice.